The street of Les Crottes in Marseille represents one type of problematic street that can be seen in most European post-industrial cities where two types of urban fabric (industrial and residential) meet. After the process of deindustrialization, the industrial side of the street cannot fulfill its function in the previously symbiotic urban system anymore and the industrial side presents a completely different morphological urban structure, breaking the consistency of the residential urban structure. Therefore, the street of Les Crottes, especially the industrial side should be the starting point of activating the whole area. The research phase of this project concentrates on finding reasons why the street of Les Crottes became like today’s situation based on morphological and typological analysis. By introducing a strategy at four different levels, this report launches at the urban level and finally ends at giving a solution at the building level of the industrial side of the street.